Mitochondrial and Metabolic Peptides in Bellevue, Washington

At Apex Health & Wellness, we specialize in therapies that enhance mitochondrial function, metabolic efficiency, and cellular energy production. Mitochondrial peptides and cofactors offer a targeted way to restore vitality, improve recovery, and reverse the cellular dysfunction that contributes to fatigue, metabolic resistance, and age-related decline.

Whether you're dealing with chronic fatigue, slow recovery, impaired glucose regulation, or oxidative stress, our protocols are designed to improve mitochondrial resilience at the cellular level — not just mask symptoms.

Signs of Mitochondrial or Metabolic Dysfunction

  • Persistent fatigue or energy crashes

  • Brain fog or cognitive fatigue

  • Weight loss resistance despite diet and exercise

  • Cold extremities or low resting body temperature

  • Poor recovery from exercise or exertion

  • Insulin resistance or blood sugar instability

  • Accelerated aging or NAD+ depletion

  • Mitochondrial dysfunction on lab or functional testing

Even subtle deficits in mitochondrial function can limit cellular repair, hormonal balance, and long-term health.

Core Peptides and Compounds for Mitochondrial Optimization

Our protocols incorporate research-backed compounds that target the mitochondria directly:

  • SS-31 (Elamipretide): Stabilizes cardiolipin in the inner mitochondrial membrane, improves ATP production, and reduces oxidative stress

  • MOTS-c: A mitochondrial-derived peptide that enhances fat oxidation, improves insulin sensitivity, and supports mitochondrial biogenesis under stress

  • Humanin: Cytoprotective peptide that may protect against mitochondrial dysfunction, apoptosis, and metabolic damage

  • 5-Amino-1MQ: Inhibits NNMT to boost NAD+ levels and enhance energy metabolism and lean body mass retention

We often combine these peptides with additional mitochondrial support compounds when appropriate:

  • Methylene Blue: Enhances electron transport chain efficiency and supports redox cycling and neuroenergetics

  • NAD+ (IV or precursors): Essential for sirtuin activation, oxidative phosphorylation, and DNA repair

  • Alpha-Lipoic Acid (ALA): A mitochondrial cofactor and antioxidant that supports glucose utilization and redox balance

  • PQQ (Pyrroloquinoline quinone): Promotes mitochondrial biogenesis and protects against oxidative stress

  • Injectable CoQ10: Improves mitochondrial energy transfer and protects against free radical damage

These interventions are selected based on your clinical profile, lab data, and goals — whether that’s improved metabolic flexibility, recovery, or healthy aging.

Our Functional Medicine Approach to Energy and Metabolism

Rather than offering one-size-fits-all protocols, we personalize mitochondrial therapy based on your specific deficits and needs. Your plan may include:

  • Targeted lab testing (fasting insulin, glucose, CRP, NAD+, homocysteine, thyroid, RBC nutrients)

  • Mitochondrial peptide or compound therapy based on symptoms and stress load

  • Nutritional and micronutrient support for mitochondrial cofactors and detoxification

  • Circadian and lifestyle alignment for mitochondrial rhythm restoration

  • Movement, light exposure, and exercise strategies to promote mitochondrial biogenesis

  • Supplementation for NAD+, glutathione status, methylation, and oxidative resilience

Mitochondria are central to the function of high-energy organs — including the heart, brain, liver, kidneys, and skeletal muscle. Impaired mitochondrial output can lead to reduced organ resilience, impaired detoxification, cognitive decline, and inflammatory signaling. By restoring mitochondrial efficiency, we help improve not just energy levels, but systemic health at the cellular level.

Conditions That May Benefit from Mitochondrial Support

  • Chronic fatigue and post-viral syndromes

  • Insulin resistance or prediabetes

  • Weight loss resistance and metabolic inflexibility

  • Mitochondrial dysfunction due to aging, stress, or toxins

  • NAD+ depletion and early aging markers

  • Cognitive fatigue or neuroenergetic decline

  • Recovery resistance from exertion or illness

  • Subclinical hypothyroidism with metabolic slowdown

Mitochondrial decline is often an invisible driver of poor performance, slow recovery, and chronic symptoms — even when labs appear "normal."

A Simple 3-Step Process to Begin

Step 1: Mitochondrial Evaluation
A 60-minute consultation exploring symptoms, metabolic history, and potential redox imbalances.

Step 2: Precision Testing (If Needed)
We may recommend labs for insulin resistance, nutrient cofactors, NAD+ status, and oxidative stress markers.

Step 3: Custom Regenerative Protocol
We build a personalized plan using mitochondrial peptides and nutraceuticals to restore cellular output and long-term function.

Important Note on Peptide Regulation

The peptides and compounds listed on this page are for informational purposes only. Availability of these therapies is subject to evolving FDA guidance and regulatory oversight.
Please contact Apex Health & Wellness directly to learn which options are currently available and appropriate for your individual needs.

Book Your Mitochondrial Optimization Consultation Today

If you're experiencing unexplained fatigue, metabolic resistance, or signs of accelerated aging, mitochondrial peptide therapy may offer a data-driven path forward.
Our goal is to restore energy, metabolic flexibility, and resilience through personalized, functional strategies.

Serving Bellevue, Seattle, and All of Washington State

Apex Health & Wellness serves clients throughout Bellevue, Redmond, Kirkland, Issaquah, and the greater Seattle area. We also offer telehealth consultations across Washington State for those seeking expert mitochondrial care from a distance.

Our clinic is built around helping patients reclaim energy, performance, and long-term wellness through advanced therapies grounded in functional medicine.